Services

Consultation

General description of peptide products. The study of patent, scientific and technological literature. Selection of peptide synthesis method. Cost price calculation.

Synthesis

Classical synthesis of peptides in solution. Solid-phase peptide synthesis. Synthesis of peptides containing more than 30 amino acid residues. Laboratory synthesis and scaling technology. Preparation of cyclic peptides, including formation of disulfide bridges. Acylation. Preparation of amides. Modification. Synthesis of fully and partially protected peptides. Peptides with non-natural amino acid residues. Preparation of reagents and intermediates for peptide synthesis. Protected amino acids: Ac, Z, Boc, Fmoc, OMe, OtBu, OBzl and others. Active esters of amino acids: ONp, ONSu, OPfp and others.

Purification

Reverse and normal-phase chromatography. Low and high pressure chromatography. Use of Ion-exchange, hydrophobic and other sorbents.

Analysis

Identity and purity of peptide products. Formation of an analytical report. Amino acid analysis. Water, acetic acid and solvents content. HPLC, LCMS, NMR, GLC, and others

Technology

Development and improvement of technology. Writing of laboratory and industrial regulations. Scheme of the technological process. Stage description of the technological process. Mass balance. Equipment. Cost calculation.

Packing

Preparation of peptide solution and lyophilizate. Packing in bottles, vials and other. Sterile filtration.

Import

Supply of peptides and reagents from world manufacturers.